Zithromax (Azithromycin)

Zithromax Review

Zithromax is used to treat many different types of bacterial infections, such as bronchitis, pneumonia, tonsillitis, skin infections, ear infections, and sexually transmitted diseases.

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Zithromax Drug Class and Mechanism

ZITHROMAX (azithromycin tablets and azithromycin for oral suspension) contain the active ingredient azithromycin, an azalide, a subclass of macrolide antibiotics, for oral administration. Azithromycin has the chemical name (2R,3S,4R,5R,8R, 10R,11R,12S,13S,14R)-13-[(2,6-dideoxy-3-C-methyl-3-O-methyl- ?-L-ribo-hexopyranosyl) oxy]-2-ethyl-3,4,10-trihydroxy-3,5,6,8, 10,12,14-heptamethyl-11-[[3,4,6-trideoxy-3- (dimethylamino)-?-D-xylo-hexopyranosyl]oxy] -1-oxa-6-azacyclopentadecan-15-one. Azithromycin is derived from erythromycin; however, it differs chemically from erythromycin in that a methyl-substituted nitrogen atom is incorporated into the lactone ring.Azithromycin, as the dihydrate, is a white crystalline powder with a molecular formula of C38H72N2O12•2H2O and a molecular weight of 785.0. .

Zithromax Uses

Azithromycin also treats sexually transmitted vaginal or urinary tract infections caused by chlamydia. It will not work for colds, flu, or other virus infections.Also used in the treatment of cystitisTake Zithromax Z-Pac Tablets by mouth. Follow the directions on the prescription label. Swallow tablets whole with a full glass of water. Zithromax tablets can be taken with or without food. Take your doses at regular intervals. Do not take your medicine more often than directed. Finish the full course prescribed by your prescriber or health care professional even if you think your condition is better. Do not stop taking except on your prescriber's advice.

Zithromax Side Effects

Most common side effects are gastrointestinal; diarrhea (5%), nausea (3%), abdominal pain (3%) and vomiting. Fewer than 1% of patients stop taking the drug due to side effects. Serious allergic reactions, nervousness, dermatologic reactions, and fatalities have been reported but are extremely rare. Increased appetite may or may not occur in the patient. As with all antimicrobial agents, pseudomembranous colitis can occur during and up to several weeks after azithromycin therapy. This drug may interfere with the effectiveness of birth control pills; other forms of contraception may be required during the treatment period. Although mild diarrhea is normal, if it is moderate to severe, or if it continues or is bothersome, check with your doctor. If you experience vomiting, or hearing loss or ringing in the ears, contact your doctor as soon as possible

Zithromax Pregnancy

Teratogenic Effects. Pregnancy Category B: Reproduction studies have been performed in rats and mice at doses up to moderately maternally toxic dose concentrations (i.e., 200 mg/kg/day). These doses, based on a mg/m2 basis, are estimated to be 4 and 2 times, respectively, the human daily dose of 500 mg. In the animal studies, no evidence of harm to the fetus due to azithromycin was found. There are, however, no adequate and well-controlled studies in pregnant women. Because animal reproduction studies are not always predictive of human response, azithromycin should be used during pregnancy only if clearly needed.

Zithromax Overdose

If overdose is suspected, contact your local poison control center or emergency room immediately. Symptoms of overdose may include irregular or unusually slow or fast heartbeat, unusual nervousness or excitement, rapid breathing, confusion, hallucinations, and seizures

Zithromax More Information

Avoid prolonged exposure to sunlight. Zithromax may increase the sensitivity of the skin to sunlight. Use a sunscreen and wear protective clothing when exposure to the sun is unavoidable.